a tool for identifying drug-targetable redox-active disulphides

Conglutinin

Intramolecular

Cysteine 347 and cysteine 361

A redox-regulated disulphide may form within Conglutinin between cysteines 347 and 361 (327 and 341 respectively in this structure).

Details

Redox score ?

83

PDB code

Structure name

structure of conglutinin carbohydrate recognition domain with glcnac- alpha-1-phosphate bound

Structure deposition date

2019-06-10

Thiol separation (Å)

2

Half-sphere exposure sum ?

69

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

347

Residue number B

361

Peptide name

Conglutinin

Ligandability

Cysteine 347 of Conglutinin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 361 of Conglutinin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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